AS Biology

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These questions from Syllabus are killing me. Please someone answer them

Q:state that a gene is a sequence of nucleotides as part of a DNA molecule, which codes for a polypeptide
and state that a mutation is a change in the sequence that may result in an altered polypeptide;


Q:describe the way in which the nucleotide sequence codes for the amino acid sequence in a polypeptide
with reference to the nucleotide sequence for HbA (normal) and HbS (sickle cell) alleles of the gene for
the β -haemoglobin polypeptide;
 
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These questions from Syllabus are killing me. Please someone answer them

Q:state that a gene is a sequence of nucleotides as part of a DNA molecule, which codes for a polypeptide
and state that a mutation is a change in the sequence that may result in an altered polypeptide;


Q:describe the way in which the nucleotide sequence codes for the amino acid sequence in a polypeptide
with reference to the nucleotide sequence for HbA (normal) and HbS (sickle cell) alleles of the gene for
the β -haemoglobin polypeptide;
I think you need to state the base substitution (gene mutation) of the nucleotides which is instead of CTT it became CAT and this changed the normal hemoglobin into sickle cell which lead to a change the β -chains of heamoglobin from carrying oxygen into useless in transporting of oxygen ...
 
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