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biology paper 1 doubts

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which disease is treated with drugs that have a similar molecular structure to DNA molecule?
A cholera
B HIV AIDS
C malaria
D tuberculosis
 
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Guys help?
12.Which features of collagen result in it having high tensile strength?
1. covalent bonds form between adjacent molecules.
2.each three stranded molecule is held together by hydrogen bonds
3.every third amino acid in the polypeptide is small
4. the primary structure is held together by peptide bonds
A 1 and 2 B 1,2 and 3 C 1,3 and 4 D 2,3 and 4

The answer is B, but why is 3 correct and why is 4 not applicable?
 
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