PLASMODIUM....and vaccine

[hassam]

its written in ms that IT IS difficult to produce vaccine against malria cos....plasmodium being eukaryotic has many genes..
i cnt understand this point and also i wanted to ask that can antibodies harm a eukaryote like plasmodium or they only work against viruses and bacteria??

 

[workinghard]

ist thing v no 4 sure is dat antibiotics are basically harmful to bacteria / prokaryotae 4 sure
about virus v can't harm dem cuz dey don't have any enzymes transcription processes out of the body so they r harmless! (u check out da mode of action of antibiotics 4m maryjones dat small diagram at the bopttom of the second last page of da chp )
about antibiotic not working against eukaryotes .. well IT IS bcuz of the no of genes
the point they are tryin 2 make here is dat even if v r able 2 harm one of its proteins eq enzyme dat is harmful there is a whole sequences of bases left behind who can make same slightly diff or all along diff antibiotics dat ll result in the same or more harm! dats how i try 2 make sense of it
and i also think being a eukaryotic it mite(not sure) hv some defense mechanism of its own!
i'l confirm all dis and tell u 2nite after askin ma mother!
u giving as or a2?

 

[bionology]

antibiotics only harm bacteria and not the viruses because they do not have cell walls, antibiotics action by preventing the cross link formation in cell walls of bacteria making them weaker and weaker, causing them to burst due to turgour pressure. Of course Viruses cannot carry out the above thing due to lack of cell walls

About the plasmodium,
it has various stages inside the human and every cell stage has a different antigen.
By the time the immune system can recognise them and make specific antibodies, they change their cell stage and so does the antigen changes. No stage lasts longer, so it is difficult to produce vaccines