a hard Biology question

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Hey guys, here is one question that I think is pretty hard and is not explained anywhere in the book. I will put it as follows:

Which statements explain why injections of vaccine may not provide protection against Vibrio cholerae?
1, V.Cholerae bacteria infect the intestine
2. The toxin produced by V.cholerae acts within the intestine
3. A vaccine providing protection against one strain of V.cholerae may not provide protection against another strain.

I think only statement 3 is valid as 1 and 2 have nothing to do with vaccination, nevertheless my teacher says the answer is 1,2 and 3.

So... Guys please help if you know the reason behind, I sincerely appreciate your help!
 
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Hey guys, here is one question that I think is pretty hard and is not explained anywhere in the book. I will put it as follows:

Which statements explain why injections of vaccine may not provide protection against Vibrio cholerae?
1, V.Cholerae bacteria infect the intestine
2. The toxin produced by V.cholerae acts within the intestine
3. A vaccine providing protection against one strain of V.cholerae may not provide protection against another strain.

I think only statement 3 is valid as 1 and 2 have nothing to do with vaccination, nevertheless my teacher says the answer is 1,2 and 3.

So... Guys please help if you know the reason behind, I sincerely appreciate your help!
In my opinion, my answer is 1 only.
Because since the Vibro Cholrae lives only in the intestine, it's difficult for the antibodies to reach the pathogen, thus vaccination is useless in this case. (I've once read this piece of information before but can't remember where exactly tbh)
 
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Hey guys, here is one question that I think is pretty hard and is not explained anywhere in the book. I will put it as follows:

Which statements explain why injections of vaccine may not provide protection against Vibrio cholerae?
1, V.Cholerae bacteria infect the intestine
2. The toxin produced by V.cholerae acts within the intestine
3. A vaccine providing protection against one strain of V.cholerae may not provide protection against another strain.

I think only statement 3 is valid as 1 and 2 have nothing to do with vaccination, nevertheless my teacher says the answer is 1,2 and 3.

So... Guys please help if you know the reason behind, I sincerely appreciate your help!

Hi, your teacher is correct. Here, this is from the Biology revision guide (pg 91: Global eradication of infectious diseases) and I think its pretty self-explanatory.

cholera.jpg
 
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