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thanxOKay sure ummm lysosomes obviously have high enzyme activity because they are just vesicles packed with hydrolytic enzymes 2. mitichondria is semi-autonomous organelle that has ribosomeS so obviously enzymes are proteins right so the more the ribosomes the more the hydrolytic activity 3. nuclei manufacture ribosomes (nucleolus) but as you can see they get out of the nucleus so is there isn't much so low activity 4. a single ribosome won't do much damage