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They didn't mention EXTREME cases of pH changes, did they? a slight Ph change does not denature the enzyme!histephenson007 said:aquariangurl said:IF the enzyme is increased along with the substrate THEN activity might increase, it's true cauze see, more substrate molecules, less no. active sites, rate of reaction decreases.histephenson007 said:why is it true??
An enzyme's activity is supposed to increase when the substrate concentration is increased
but the statement doesn't mention that there are a limited number of enzymes. So lets think that there is a constant amount of enzymes. starting from zero substrate concentration, if we increase the substrate concentration, the rate of reaction is going to increase. cuz more substrate molecules can form an enzyme-substrate complex with the enzymes. (instead of some enzymes having to wait for a substrate molecule to collide with its active site)
Also, if we change the pH of the solution, the enzyme will be denatured too. So, it WILL be inactivated!