I deleted my other post, because i think i did it wrong. Look at the reaction from the one top to the one below....this is the fragmentation occurring.There is a question in the pastpapers that says an enzyme will hydrolyze the hinge region of antibodies and break the antibodies into "3" fragments. How can they break into 3????? Shouldn't the antibodies break into 2 parts each contains one heavy chain and one light chain if hydrolysis occurs at the hinge region??