Can someone please explain the full process of an immune response? as in the order of how everything happens and which cells reach the pathogen first?
Primary response
1) the pathogen invades the body
2) it damages or weakens body cells
3) the weakened body cells produce proteins called histamines
4) the phagocytes in the blood are attracted to these proteins...(chemotaxis)
5) the phagocytes (macrophages) engulf the pathogen by phagocytosis and display the non self antigens on its surface
6) the T helper cells with the complementary receptors goes and recognizes the antigens of the pathogen, and secretes chemicals which cause the bone marrow to form T Killer cells, and secretes cytokines (hormone-like)
7) B lymphocytes with the complementary surface receptors are activated due to these cytokines and divide by mitosis to produce B-memory cells and Plasma cells.
8) The B memory cells further divide to produce more memory cells and plasma cells.
9) the plasma cells release anitbodies with the variable region (antigen binding site) complementary to the antigens of the pathogen. These antibodies destroy the pathogens.
10) The T killer cells (cytotoxic T cells) with the specific complementary receptors release chemicals such as hydrogen peroxide or punch holes in the infected body cells to remove and kill any remaining weakened body cells, and the remaining debris.
11) The memory B and memory T cells remain circulating in the blood.
Secondary response:
The memory cells which are in the blood on the encounter of the pathogen with the antigens complementary to their receptors, divide rapidly producing plasma cells which secrete antibodies (more than the primary response) and the pathogens are destroyed in a short time.
Correct me if im wrong